English Abstract
ABSTRACT:
Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy. In two-thirds of patients,
it is preceded by an upper respiratory or gastrointestinal tract infection. Temporally associated cases of
GBS following COVID-19 vaccination have been described with different COVID-19 vaccines. In this study,
we report three cases of GBS patients following COVID-19 vaccine. Two of the studied patients received
the Sinopharm vaccine and one patient received the AstraZeneca vaccine. All patients were diagnosed
with acute motor axonal neuropathy (AMAN) type of GBS, on nerve conduction studies. All three patients
responded well to treatment with intravenous immunoglobulin (IVIg). The association between COVID-19
vaccination and GBS is not well understood and more studies are needed to establish whether it is merely
an association or a causal relationship.
