Abstract: The world is changing swiftly. These changes require leaders to possess new kinds of knowledge and skills to understand and deal with such complex trends. Therefore, this chapter explains the Leadership Intelligence, that incorporates Intelligence Quotient (IQ), Emotional Quotient (EQ), Cultural Quotient (CQ) and Spiritual Quotient (SQ), for a leading organization, that has significant uncertainty and complexity. With the growing uncertainty and complexity in business environmental contexts, leadership roles have become paramount. And thus, this paper proposes a leadership intelligence framework that incorporates IQ, EQ, CQ, and SQ elements, based on current literature. Consequently, 21st Century leaders should have these leadership intelligence qualities as a secret of leadership success, in today's organizations, particularly during turbulent times. To achieve higher leadership intelligence, global leaders must recognize their emotional stability along with cognitive balance and work according to local cultural patterns as well as spiritual norms by developing superior IQ, EQ, CQ, and SQ. Basically, this paper discusses why IQ, EQ, CQ, and SQ are essential for today's leaders who face demanding situations in which they must anticipate and adapt to changes and address wicked problems. Moreover, in the present 21st Century global setting, leaders must own different thinking skills and higher intelligence levels to achieve higher standards of leadership. In these challenging, complex situations, standardized leadership approaches often do not work. New leadership intelligence is needed, to deal with the complex changes.